The drug should emerge as a first-line therapy for persons with type 2 diabetes and associated overweight/obesity as well as atherosclerotic cardiovascular disease
[1] How It Works in Laboratory Models GHS-R1a is a G-protein-coupled receptor first identified in pituitary and hypothalamic tissue
Side effects tend to be dose-dependent and include nausea, vomiting, abdominal cramps, diarrhea, and a fishy body odor
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Prescribing information notes that semaglutide- and tirzepatide-treated patients may have increases in amylase or lipase without pancreatitis and that the meaning of an isolated increase may be uncertain
